Dr. Gregory Haljan is leading a clinical trial of a COVID-19 antibody. (Contributed photo)

Dr. Gregory Haljan is leading a clinical trial of a COVID-19 antibody. (Contributed photo)

B.C.-based clinical trial of COVID-19 antibody ‘very promising,’ says expert

Participation criteria expanded for infusion clinic based at Peace Arch Hospital

The clinical trial of a drug that one expert says looks “very promising” for use in stopping the progression of COVID-19 moved into a new phase this week, with the opportunity to participate now open to all eligible patients in the Fraser Health region.

Dr. Gregory Haljan – head of Surrey Memorial Hospital’s critical care unit and Fraser Health’s regional medical director for research – said Monday (April 26) that around 300 COVID-19-positive patients are sought to receive the medication bamlanivimab as part of the B-EPIC (Bamlanivimab-Emergency Passive Immunity in COVID-19) study.

READ MORE: Clinical trial of COVID-19 drug for severe cases to be carried out at Surrey hospital

Designed in January, the study aims to determine if the antibody can prevent those who get COVID-19 from getting so sick they need to be hospitalized – and if it can, “well, we really need that right now,” Haljan said.

“We’re in the third wave,” Haljan said of the pandemic. “This is the worst it’s been (in the SMH intensive care unit) yet. We’re working about as hard as we can right now in the ICU.

“This third wave has been a real kick in the pants.”

Researchers also want to learn if bamlanivimab can reduce the long-term effects of the illness.

Its use for COVID-19 treatment in high-risk patients has interim approval from Health Canada. The drug is designed to block the COVID-19 virus from attaching to and entering cells, thus potentially preventing the illness from worsening in newly diagnosed patients.

“Once you get an infection, it’s too late for a vaccine to work,” Haljan said. “What we want to do is provide those antibodies (that a vaccine typically triggers a body to produce) early in the disease, to give the immune system a head start.”

Recruiting for the study opened in March to residents of Surrey, White Rock and Delta. It then expanded to include patients living in Burnaby, Langley, Maple Ridge and Pitt Meadows.

Haljan said participants must begin the therapy within three days of a positive COVID-19 test, or within 10 days of their first symptoms.

Eligible participants are those 65 and older, or between 18 and 64 years old who have tested positive for COVID-19 and have at least one illness or condition that puts them at risk of being hospitalized for COVID-19 infection.

Haljan hopes to recruit up to 20 patients per day over the next two weeks, in order to complete the study by May 9.

Currently, the medication is being delivered at an infusion clinic set up at Peace Arch Hospital, but Haljan said the hope is to establish more clinics this week, particularly in the Fraser East area.

He emphasized that while the medication only has interim approval, it is “very safe,” and, it has been found to “retain activity” against the U.K variant of COVID-19; the most prevalent variant in Canada.

READ MORE: U.K variant of coronavirus detected at seven schools in Surrey, Delta

The study, he noted, “is asking questions nobody else in the world is asking right now about this drug.”

To sign up or for more information, visit www.bepicstudy.ca



tholmes@peacearchnews.com
Like us on Facebook and follow us on Twitter

CoronavirusSurreywhite rock

Just Posted

Tents set up under the Trail Skywalk earlier this spring. Photo: Trail Times
Message from Concerned Trail Citizens: ‘A Necessary Response’

” … if we are not part of the solution, we are part of the problem.”

“Think on These Things” is a column written by retired Creston pastor Ian Cotton. (File photo)
Think on These Things: Everyone is Invited

“Tell them there is healing, cleansing for every soul…”

Swiss guard at Vatican City. The Pontifical Swiss Guard is a minor armed forces and honour guards unit maintained by the Holy See that protects the Pope and the Apostolic Palace, serving as the de facto military of Vatican City. Photo: Etienne Girardet on Unsplash
News from The Vatican

Pope Francis issued a law decreeing that women can be installed in the lay ministries of lectors

North Okanagan business Hytec Kohler set up a COVID-19 vaccination clinic at the Spallumcheen plant Friday, May 14. (Jennifer Smith - Morning Star)
More than half of eligible adults in Interior Health vaccinated

Over 365,000 vaccine doses have been administered throughout the Interior Health region

Student-nurse Kendra Waterstreet administers the Pfizer vaccine to Litia Fleming at the Waneta Plaza vaccination clinic in the old Zellers buiding. Photo: Jim Bailey
Trail vaccination clinic readies for adults age 40+

B.C.’s state of emergency is extended through the end of day on May 25

Daily confirmed COVID-19 cases reported to B.C. public health, seven-day rolling average in white, to May 12, 2021. (B.C. Centre for Disease Control)
B.C. preparing ‘Restart 2.0’ from COVID-19 as June approaches

Daily infections fall below 500 Friday, down to 387 in hospital

A vial of AstraZeneca vaccine is seen at a mass COVID-19 vaccination clinic in Calgary, Alta., Thursday, April 22, 2021. Dr. Ben Chan remembers hearing the preliminary reports back in March of blood clots appearing in a handful of European recipients of the Oxford-AstraZeneca COVID-19 vaccine. THE CANADIAN PRESS/Jeff McIntosh
Science on COVID, VITT constantly changing: A look at how doctors keep up

While VITT can represent challenges as a novel disorder, blood clots themselves are not new

Poached trees that were taken recently on Vancouver Island in the Mount Prevost area near Cowichan, B.C. are shown on Sunday, May 10, 2021. Big trees, small trees, dead trees, softwoods and hardwoods have all become valuable targets of tree poachers in British Columbia as timber prices hit record levels. THE CANADIAN PRESS/Jen Osborne.
Tree poaching from public forests increasing in B.C. as lumber hits record prices

Prices for B.C. softwood lumber reached $1,600 for 1,000 board feet compared with about $300 a year ago

The warm weather means time for a camping trip, or at least an excursion into nature. How much do you know about camps and camping-related facts? (John Arendt - Summerland Review)
QUIZ: Are you ready to go camping?

How many camp and camping-related questions can you answer?

On Friday, May 14 at Meadow Gardens Golf Club in Pitt Meadows, Michael Caan joined a very elite club of golfers who have shot under 60 (Instagram)
Crowds at English Bay were blasted with a large beam of light from an RCMP Air-1 helicopter on Friday, May 14. THE CANADIAN PRESS/Marc Grandmaison
Police enlist RCMP helicopter to disperse thousands crowded on Vancouver beach

On Friday night, police were witness to ‘several thousand people staying well into the evening’

People shop in Chinatown in Vancouver on Friday, February 5, 2021. THE CANADIAN PRESS/Jonathan Hayward
Vancouver community leaders call for action following 717% rise in anti-Asian hate crimes

‘The alarming rise of anti-Asian hate in Canada and south of the border shows Asians have not been fully accepted in North America,’ says Carol Lee

Sinikka Gay Elliott was reported missing on Salt Spring Island on Wednesday, May 12. (Courtesty Salt Spring RCMP)
Body of UBC professor found on Salt Spring Island, no foul play suspected

Sinikka Elliott taught sociology at the university

The first Black judge named to the BC Supreme Court, Selwyn Romilly, was handcuffed at 9:15 a.m. May 14 while walking along the seawall. (YouTube/Screen grab)
Police apologize after wrongly arresting B.C.’s first Black Supreme Court Justice

At 81 years old, the retired judge was handcuffed in public while out for a walk Friday morning

Most Read