Benadryl is pictured at a home in North Vancouver, B.C., Monday, November, 11, 2019. THE CANADIAN PRESS/Jonathan Hayward

Benadryl is pictured at a home in North Vancouver, B.C., Monday, November, 11, 2019. THE CANADIAN PRESS/Jonathan Hayward

Moving Benadryl behind the counter doesn’t resolve safety concerns: pharmacists

More doctors are warning against older antihistamines, such as the active ingredient in Benadryl

Sally McQuinn once kept her medicine cabinet stocked with Benadryl, the go-to medication to treat her daughter’s multiple allergies: the Ottawa mother of three assumed that because it was sold on pharmacy shelves and didn’t require a prescription, it was safe.

But she was surprised by recent headlines highlighting that a growing number of doctors are warning against the use of older antihistamines, such as diphenhydramine, the active ingredient in Benadryl, because of safety and efficacy concerns.

McQuinn says she will no longer buy Benadryl and instead choose from the number of existing alternatives.

“Nobody wants to choose the one that’s going to have more negative consequences,” she explains.

The Canadian Society of Allergy and Clinical Immunology released a statement in October recommending curbing the use of older first-generation antihistamines in both adults and children. They said newer antihistamines, including Reactine, Aerius, and Claritin, are safer.

Long-known side effects from standard doses of Benadryl include sedation, cognitive impairment, and possible heart rhythm abnormalities.

Children are particularly at risk of severe consequences, such as seizures and coma, from too high a dose, and research suggests teens using Benadryl for allergies have lower scores on exams than their peers.

The CSACI statement called on regulators to consider moving Benadryl and other first-generation antihistamines from pharmacy shelves to behind the counter in order to force an interaction with pharmacists who can explain the issues and suggest alternatives.

Pharmacists, however, say the solution isn’t so simple: putting Benadryl behind the counter, they say, is not practical and won’t resolve the safety concerns. And they have the same concerns about many other over-the-counter drugs.

READ MORE: Canadian allergists’ group wants Benadryl behind the counter due to side effects

Consumers would have to speak to a pharmacist, who could decline to provide the medication. But since the drug is approved by Health Canada and is well known, many consumers, will continue to push for it, says pharmacist Barry Power, a spokesman for the Canadian Pharmacists Association.

That can create conflict at the drugstore, he adds.

“For many people, the side effect profile isn’t a big concern. But if Benadryl were to come on the market today, it might require a prescription, because of the safety profile,” he says.

Benadryl’s maker, Johnson & Johnson says the products are approved by Health Canada and “when used as directed, are safe and effective.”

In a statement, Health Canada said products containing diphenhydramine meet the requirements and regulations of the Food and Drugs Act. It says it is assessing the allergists’ recent statement “to determine if further risk mitigation measures for diphenhydramine-containing products are required.”

The agency says that it continues to monitor scientific and medical information as it evolves and would take action if this information required a change to “the regulatory status of products containing diphenhydramine.”

Currently, Benadryl is approved for sale without a prescription in locations where a pharmacist is present. This means that it can be sold in pharmacies and certain grocery stores, but not in convenience stores or gas stations.

Nardine Nakhla, a pharmacist who teaches at the University of Waterloo in Ontario, says moving all the diphenhydramine-containing drugs behind the counter is “unrealistic … due to the sheer number of products that contain these problematic ingredients.”

Nakhla says there are also many other drugs, besides diphenhydramine, that have similar risk profiles and are available on pharmacy shelves.

Power agrees that the issue of which drugs belong behind the counter “becomes a bigger question as you start looking (at it).”

– Dr. Michelle Ward is a pediatrician at the Children’s Hospital of Eastern Ontario and associate professor at the University of Ottawa

The Canadian Press

Like us on Facebook and follow us on Twitter

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Elvira D’Angelo, 92, waits to receive her COVID-19 vaccination shot at a clinic in Montreal, Sunday, March 7, 2021, as the COVID-19 pandemic continues in Canada and around the world. THE CANADIAN PRESS/Graham Hughes
110 new cases of COVID-19 in Interior Health

Provincial health officers announced 1,005 new cases throughout B.C.

Tala MacDonald, a 17-year-old student at Mount Sentinel Secondary who is also a volunteer firefighter, has won the $100,000 Loran Scholarship. Photo: Submitted
West Kootenay student wins $100K scholarship

Tala MacDonald is one of 30 Canadians to receive the Loran Scholarship

Montrose resident Kimba McLean has hiked Antenna Trail every day since October and counting. Photo: Jim Bailey
Montrose man makes daily trek up Antenna Trail

Kimba McLean put on more than 800-km hiking Antenna Trail every day for the past six months

Kristian Camero and Jessica Wood, seen here, co-own The Black Cauldron with Stephen Barton. The new Nelson restaurant opened earlier this month while indoor dining is restricted by the province. Photo: Tyler Harper
A restaurant opens in Nelson, and no one is allowed inside

The Black Cauldron opened while indoor dining is restricted in B.C.

First-year Selkirk College student Terra-Mae Box is one of many talented writers who will read their work at the Black Bear Review’s annual (virtual) launch on April 22. Photo: Submitted
Rainbow trouts thrashing with life as they’re about to be transferred to the largest lake of their lives, even though it’s pretty small. These rainbows have a blue tinge because they matched the blue of their hatchery pen, but soon they’ll take on the green-browns of their new home at Lookout Lake. (Zoe Ducklow/News Staff)
VIDEO: B.C. lake stocked with hatchery trout to delight of a seniors fishing club

The Cherish Trout Scouts made plans to come back fishing soon

An Extinction Rebellion Vancouver Island (XRVI) climate change event in 2019 saw a large crowd occupy the Johnson Street bridge. Black Press File Photo
‘In grief for our dying world’: B.C. climate activists embark on 4-day protest

The four-day trek on foot and by ferry will see them end at the legislature

A vial of some of the first 500,000 of the two million AstraZeneca COVID-19 vaccine doses that Canada secured. THE CANADIAN PRESS/Carlos Osorio
Canada’s 2nd blood clot confirmed in Alberta after AstraZeneca vaccine

Thw male patient, who is in his 60s, is said to be recovering

An Interior Health nurse administers Pfizer-BioNTech COVID-19 vaccines to seniors and care aids in Kelowna on Tuesday, March 16. Photo: Phil McLachlan/Kelowna Capital News
Interior Health opens up vaccine eligibility in Columbia Valley to 18 years or older

Only local residents can register and book appointments as COVID-19 case counts spike in the region

Valen a student of Coldstream Elementary writes advice for adults amid a pandemic.
‘We can get rid of COVID together’: B.C. kids share heartwarming advice

Elementary students share their wisdom to adults in unprecedented times

The funeral of Britain’s Prince Philip in Windsor, England, on Saturday, April 17, 2021. Philip died April 9 at the age of 99. (Kirsty Wigglesworth/AP)
PHOTOS: Prince Philip laid to rest Saturday as sombre queen sits alone

The entire royal procession and funeral took place out of public view within the grounds of Windsor Castle

B.C. Health Minister Adrian Dix and Premier John Horgan describe vaccine rollout at the legislature, March 29, 2021. (B.C. government)
B.C. health minister says delay in Moderna vaccine ‘disappointing’

‘The sooner we get vaccines in people’s arms the better, and inconsistency in delivery is a consistent problem. This is simply a reality and not an issue of blame,’ Adrian Dix said Friday

(Police handout/Kamloops RCMP)
B.C. man dies in custody awaiting trial for Valentine’s Day robbery, kidnapping spree

Robert James Rennie, who was on the Kamloops RCMP’s most wanted list, passed away at the North Fraser Pretrial Centre in Coquitlam

Photos of Vancouver Canucks players are pictured outside the closed box office of Rogers Arena in downtown Vancouver Thursday, April 8, 2021. THE CANADIAN PRESS/Jonathan Hayward
Canucks to return to play Sunday versus Leafs after COVID-19 outbreak

The team has had 11 games postponed since an outbreak late last month

Most Read